In the past 10 years, many studies have been published on the development of the enteric nervous system. These studies have included a broad diversity of approaches including mathematical modelling, genetic studies of humans with Hirschsprung’s disease, and genetic, cell and molecular biological studies using laboratory animals. Recent studies have also shown that neural stem cells can be isolated from the developing and adult enteric nervous systems, and there is enormous interest in the use of these enteric neural stem cells for therapeutic purposes.
This meeting will provide an opportunity to take stock of the progress that has been made in understanding how the enteric nervous system develops, and to discuss the many questions that remain unanswered.
The meeting will also be valuable for researchers interested in Sox10, Ret signaling and endothelin signaling in general. |