de Iongh Lab ~ Publications

Zariwala MA, Leigh MW, Ceppa F, Kennedy MP, NooneP G,.Carson JL, Hazucha MJ, Lori1 A, Horvath J, Olbrich H, Loges NT, Bridoux A-M, Pennarun G, DuriezB, EscudierE, Mitchison HM, Chodhari R, Chung EMK, Morgan LM, de Iongh RU, Rutland J, Pradal U, Omran H, Amselem S,. Knowles MR. (2006). Mutations of DNAI1 in Primary Ciliary Dyskinesia: Evidence of founder effect in a common mutation. Am J Respir Crit Care Med, 174(8):858-66

Wederell ED, Lovicu FJ, McAvoy JW, de Iongh RU. Altered integrin expression and signaling in a model for anterior subcapsular cataract. Am J Pathol (submitted).

Kokkinos MI; Brown, HJ; de Iongh RU. (2006). Focal adhesion kinase expression and activation during lens development.  Mol Vis, (Accepted).

de Iongh RU, Abud HE, Hime GR. (2006). Wnt/Frizzled signaling in eye development and disease.  Front Biosci 11:2442-64.

de Iongh RU, Wederell E, Lovicu FJ, McAvo y JW. (2005). TGFß-induced EMT in the lens: a model for cataract formation. Cells Tissues & Organs 179:43-55.

de Iongh RU, Chen Y, Kokkinos MI, McAvoy JW. (2004). BMP and activin receptor expression in lens development. Mol Vis, 10:566-76.

Stump RJW, Ang S, Chen Y, von Bahr T, Lovicu FJ, Pinson K, de Iongh RU, Yamaguchi TP, Sassoon DA, McAvoy JW. (2003). A role for Wnt/ß-catenin signaling in lens epithelial differentiation. Dev Biol. 259:48-61.

de Iongh, R. U., Lovicu, F. J, Overbeek, P. A., Schneider, M. D., Joya, J., Hardeman, E. and McAvoy, J. W. (2001). Requirement for TGF-ß receptor signaling during terminal lens fibre differentiation. Development, 128:3995-4010.

de Iongh RU, Gordon-Thomson C, Hales AM, Chamberlain CG, McAvoy JW. (2001). TGF-ß receptor expression in the lens: implications for differentiation and cataractogenesis. Exp Eye Res, 72:649-659.

McAvoy JW, Chamberlain CG, de Iongh RU, Hales AM, Lovicu FJ. (2000). Peter Bishop Lecture: growth factors in lens development and cataract: key roles for FGF and TGF-ß. Clin Exp Ophthalmol, 28:133-139.

McAvoy JW, Chamberlain CG, de Iongh RU, Hales AM, Lovicu FJ. (1999). Lens development, Eye, 13:425-437.

Gordon -Thomson C, de Iongh RU, Hales AM, Chamberlain CG, McAvoy JW. (1998). Differential cataractogenic potency of TGF-ß 1, TGF-ß 2 and TGF-ß 3 and their expression in the postnatal rat eye. Invest Ophthalmol Vis Sci, 39:1399-1409.

de Iongh RU, Lovicu FJ, Chamberlain CG, McAvoy JW. Differential expression of FGF receptors during rat lens morphogenesis and growth. Invest Ophthalmol Vis Sci, 1997;38:1688-1699.

Lovicu FJ, de Iongh RU, McAvoy JW, (1997). Expression of FGF-1 and FGF-2 mRNA during lens morphogenesis, differentiation and growth. Curr Eye Res, 16:222-230.

de Iongh RU, Lovicu FJ, Hanneken A, Baird A, McAvoy JW. (1996). FGF receptor-1 (flg) expression is correlated with fibre differentiation during rat lens morphogenesis and growth. Dev Dynam, 206:412-426.

Schulz MW, Chamberlain CG, de Iongh RU, McAvoy JW. (1993). Acidic and basic FGF in ocular media and lens: implications for lens polarity and growth patterns. Development, 118:117-126.

de Iongh RU, McAvoy JW. (1993). Cellular localisation of aFGF during early lens development by a triple fluorescent labelling technique. J Comput Assist Microsc, 5:31-36.

de Iongh R, McAvoy JW. (1992). Distribution of acidic and basic fibroblast growth factors (FGF) in the foetal rat eye: implications for lens development. Growth Factors, 6:159-177.

McAvoy JW, Chamberlain CG, de Iongh RU, Richardson NA, Lovicu FJ. (1991). The role of fibroblast growth factor in eye lens development. Ann NY Acad Sci, 638:256-274.