Hime Lab ~ Selected Publications
MONK AC, SIDDALL NA, VOLK T, FRASER B, QUINN LM, McLAUGHLIN EA, HIME GR. (2010) HOW is required for stem cell maintenance in the Drosophila testis and for the onset of transit-amplifying divisions. Cell Stem Cell 6(4): 348-360.
SIDDALL NA, LIN JI, HIME GR, QUINN LM. (2009) Myc – what we have learned from flies. Current Drug Targets 10(7): 590-601.
EID JP, ARIAS AM, ROBERTSON H, HIME GR, DZIADEK M. (2008) The Drosophila STIM1 orthologue, dSTIM, has roles in cell fate specification and tissue patterning. BMC Developmental Biology 8:104.
HIME GR, LOVELAND KL, ABUD HE. (2007) Drosophila spermatogenesis: insights into testicular cancer. International Journal of Andrology 30(4): 265-274.
HOLT JE, LY-HUYNH JD, EFTHYMIADIS A, HIME GR, LOVELAND KL, JANS DA. (2007) Current Genomics 8(5): 323-334.
de IONGH RU, ABUD HE, HIME GR. (2006) WNT/Frizzled signalling in eye development and disease. Frontiers in Bioscience 11: 2442-2464.
SIDDALL NA, McLAUGHLIN EA, MARRINER NL, HIME GR. (2006) The RNA-binding protein Musashi is required intrinsically to maintain stem cell identity. Proceedings of the National Academy of Sciences of the USA 103(22): 8402-8407.
SZCZEPNY A, HIME GR, LOVELAND KL. (2006) Expression of hedgehog signalling components in adult mouse testis. Developmental Dynamics 235(11): 3063-3070.
BROWN CM, HIME GR, KOOPMAN P, LOVELAND KL. (2005) Genetic basis of human testicular germ cell cancer: insights from the fruitfly and mouse. Cell Tissue Research 322(1): 5-19.
LOVELAND KL, HIME G. (2005) TGFbeta superfamily members in spermatogenesis: setting the stage for fertility in mouse and Drosophila. Cell Tissue Research 322(1): 141-146.
BUNT, S.M. AND HIME, G.R. (2004) Ectopic activation of Dpp signalling in the male Drosophila germline inhibits germ cell differentiation. Genesis 39, 84-93
QUINN, L.M.; DICKINS, R.A.; COOMBE, M.; HIME, G.R.; BOWTELL, D.D.L.; RICHARDSON, H.R. (2004) Drosophila Hfp negatively regulates dmyc and stg to inhibit cell proliferation. Development 131, 1411-1423
HIME, G.R., LADA, H., FIETZ, M.J., GILLIES, S., PASSMORE, A., WICKING, C. AND WAINWRIGHT, B.J. (2004) Functional analysis in Drosophila indicates that the NBCCS/PTCH1 mutation G509V results in activation of smoothened through a dominant-negative mechanism. Developmental Dynamics 229, 780-790
HIME, G.R., ABUD, H.E., GARNER, B., HARRIS, K-L. AND ROBERTSON, H. (2001) “ Dynamic expression of alternate splice forms of D-cbl during embryogenesis.” Mechanisms of Development 102, 235-238
BRILL, J.A.; HIME, G.R.; SCHARER-SCHUKSZ, M. AND FULLER, M.T. (2000) “ A phospholipid kinase regulates actin organization and intercellular bridge formation during germline cytokinesis.” Development 127, 3855-3864
ROBERTSON, H.; HIME, G.R. AND BOWTELL, D.D.L. (2000) “A Drosophila analogue of v-Cbl is a dominant-negative oncoprotein in vivo.” Oncogene 19, 3299-3308
WARREN, W.D.; LIN, E.; VUONG, T.; HIME, G.R. AND MCKAY, M.J. (2000) “A Drosophila rad21 homologue, drad21, is expressed in S-phase mitotic cells.” Gene 250, 77-84
FABRIZIO, J.J.; HIME, G.; LEMMON, S.K. AND BAZINET, C. (1998) Genetic dissection of sperm individualization in Drosophila melanogaster. Development 125, 1833-1843
KILIAN, A.; BOWTELL, D.D.L.; ABUD, H.E.; HIME, G.R.; VENTER, D.J.; KEESE, P.K.; DUNCAN, E.L.; REDDEL, R.R. AND JEFFERSON, R.A. (1997) Isolation of a candidate for the human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types. Human Molecular Genetics 6(12), 2011-2019.
HIME, G.R.; PAI DHUNGAT, M.; NG, A.; BOWTELL, D. (1997) D-Cbl, the Drosophila homologue of the c-Cbl proto-oncogene, interacts with the Drosophila EGF receptor in vivo, despite lacking C-terminal adaptor binding sites. Oncogene 14, 2709-2719.
HIME, G.R.; BRILL, J.A.; FULLER, M.T. (1996) Assembly of ring canals in the male germ line from structural components of the contractile ring. Journal of Cell Science 109, 2779-2788.