Vincan Lab ~ Selected Publications
~Publications.
- Amin N, Vincan E (2012). The Wnt signalling pathways and cell adhesion. Front Biosci in press
- Cheasley D, Pereira L, Lightowler S, Vincan E, Malaterre J, Ramsay RG (2011). c-Myb Controls Intestinal Stem Cells. Stem Cells, Epub Oct 13. doi: 10.1002/stem.761
- Byun DS, Ahmed N, Nasser S, Shin J, Al-Obaidi S, Goel S, Corner GA, Wilson AJ, Flanagan DJ, Williams DS, Augenlicht LH, Vincan E, Mariadason JM (2011) Intestinal epithelial-specific PTEN inactivation results in tumor formation. American J Pathology, Epub August 11, 2011
- Mrkusich EM, Flanagan DJ, Whitington PM (2011) The core planar cell polarity gene prickle interacts with flamingo to promote sensory axon advance in the Drosophila embryo. Dev Biol. 358:224-30.
- Sakthianandeswaren A, Christie M, D’Andreti C, Tsui C, Jorissen R, Li S,Fleming N, Gibbs P, Lipton L, Malaterre J, Ramsay RG, Phesse TJ, Ernst M, Jeffery RE, Poulsom R, Leedham SJ, Segditsas S, Tomlinson IPM, Bernhard OK, Simpson RJ, Walker F, Faux M, Church N, Catimel B, Flanagan DJ, Vincan E, and Sieber OM (2011). PHLDA1 expression marks the putative epithelial stem cells and contributes to tumor progression in the human intestine. Cancer Research 71:3709-3719.
- Vincan E, Flanagan DJ, Pouliot N, Brabletz T, Spaderna S (2010). Variable FZD7 expression in colorectal cancers indicates regulation by the tumour microenvironment. Dev Dynamics239:311-317.
- Vincan E, Barker N (2008). The upstream components of the Wnt signalling pathway in the dynamic EMT and MET associated with colorectal cancer progression. Clin Exp Metastasis 25:657-63
- Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, Spaderna S, Brabletz T (2008). A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep 9:582-9
- Huynh D, Vincan E, Mantamadiotis T, Purcell D, Chan C-K, Ramsay RG (2007). Oncogenic properties of HIV-Tat in colorectal cancer cells. Current HIV Research5:403-409
- Vincan E, Brabletz T, Faux MJ, Ramsay RG (2007). A human three-dimensional organoid model allows the study of dynamic and reversible EMT and MET that underpins colorectal carcinogenesis. Cells Tissues Organs185:20-28
- Vincan E, Swain RK, Brabletz T, Steinbeisser H (2007). Frizzled7 dictates embryonic morphogenesis: implications for colorectal cancer progression. Frontiers in Bioscience12:4558-4567
- Vincan E, Darcy PK, Farrelly CA, Faux M, Brabletz T and Ramsay RG (2007). Frizzled-7 dictates three-dimensional organization of colorectal cancer cell carcinoids. Oncogene 26:2340-2352
- Vincan E, Darcy PK, Smyth MJ, Thompson EW, Thomas RJS, Phillips WA, Ramsay RG (2005). Frizzled-7 receptor ectodomain expression in a colon cancer cell line induces morphological change and attenuates tumor growth. Differentiation 73:142-153
- Ramsay RG, Micallef SJ, Williams B, Lightowler S, Vincan E, Heath JK, Mantamadiotis T, Bertoncello I (2004). Colony-stimulating factor-1 promotes clonogenic growth of normal murine colonic crypt epithelial cells in vitro. J Interferon Cytokine Research 24:416-427
- Vincan E (2004). Frizzled/Wnt Signalling: The Insidious Promoter of Tumour Growth and Progression. Frontiers in Bioscience9:1023-1034
- Philp A, Campbell I, Leet CSF, Vincan E, Rockman SP, Thomas RJS, Whitehead RH, Phillips WA (2001) The phosphatidylinositol 3-kinase p85a gene subunit is an oncogene in human ovarian and colon tumours. Cancer Research 61:7426-7429
- Currie SA, Rockman SP, Ciavarella M, Vincan E, Dow C, Thomas RJS, Phillips WA (2001). Id2 is a target of the b-catenin/TCF4 pathway in colon carcinoma. J Biological Chemistry 276:45113-45119
- Sully V, Pownall S, Vincan E, Bassal S, Borowski AH, Hart PH, Rockman SP, Phillips WA (2001). Functional abnormalities in protein tyrosine phosphatasee-deficient macrophages. Biochem Biophys Res Com286:184-188
- Dimitriadis A, Vincan E, Mohammed IM, Roczo N, Phillips WA, Baindur-Hudson S (2001). Expression of Wnt genes in human colon cancers. Cancer Letters166:185-191
- Vincan E, Leet CSF, Reyes NI, Dilley RJ, Thomas RJS, Phillips WA (2000). Sodium butyrate-induced differentiation of human LIM2537 colon cancer cells decreases GSK-3b activity and increases levels of both membrane-bound and APC/Axin/GSK-3b complex-associated pools of b-catenin. Oncology Research12:193-201
- Philp AJ, Phillips WA, Rockman SP, Vincan E, Burns W, Banidur-Hudson S, Thomas RJS (2000). Microsatellite Instability in Gastrointestinal Tract Tumours. Int J Surg Invest 2:267-274
- Du X-J, Vincan E, Percy E, Wang BH, Woodcock EA (2000). Enhanced negative chronotropy by inhibitory receptors in transgenic heart over-expressing b2-adrenergic receptors. J Autonom Nerv Syst 79:108-116
- Leet CSF, Vincan E, Thomas RJS, Phillips WA (1999). Lipopolysaccharide-induced priming of the human neutrophil is not associated with a change in phosphotyrosine phosphatase activity. Int J Biochem Cell Biol 31:585-593
- Du X-J, Vincan E, Woodcock DM, Milano CA, Dart AM, Woodcock EA (1996). Response to cardiac sympathetic activation in transgenic mice overexpressing b2-adrenergic receptor. American J Physiology 271:H630-636
- Vincan E, Neylon CB, Jacobsen AN, Woodcock EA (1996). Reduction in Gh protein expression is associated with cytodifferentiation of vascular smooth muscle cells. Molecular Cellular Biochemistry 157:107-110
- Vincan E, Neylon CB, Graham RM, Woodcock EA (1995). Isolation of neonatal cardiomyocytes reduces the expression of the GTP-binding protein, Gh. J Molecular Cellular Cardiology 27:2393-2396
- Neate EV, Greenhalgh AM, McPhee DA, Crowe SM (1992). Bacterial lipopolysaccharide mediates the loss of CD4 antigen from the surface of purified peripheral blood monocytes. Clin Exp Immunol 90:539-544
- Healey DS, Maskill WJ, Neate EV, Beaton F, Gust ID (1998). A preliminary evaluation of five commercial HIV antigen detection assays. J Virol Methods 20:115-125
- Neate EV, Pringle RC, Jowett JBM, Healey DS, Gust ID (1987). Isolation of HIV from Australian patients with AIDS, AIDS related conditions and healthy antibody positive individuals. Aust NZ J Med17:461-466
- Neate EV, Boyle W (1986). A rapid colorimetric assay for measuring MLR. Transplant Proc 18:340-342
~Book Chapters:
- Vincan E, Whitehead RH, Faux MC (2008). Analysis of Wnt/FZD-Mediated Signalling in a Cell Line Model of Colorectal Cancer Morphogenesis. Methods in Molecular Biology468:263-73.
~Feature issues:
- ‘Wnt/FZD signalling in cancer and disease.’ Managing Editor, Vincan E (2005-ongoing), Special issue for Frontiers in Bioscience. http://www.bioscience.org/current/special/vincan.htm
~Books:
- ‘Wnt signaling’, Volume 1, Pathway Methods and Mammalian Models, Vol. 468, Methods in Molecular Biology, Humana Press, USA (2008). Editor, Dr E Vincan; Series Editor Prof J Walker. Book doi: 10.1007/978-1-59745-249-6
- ‘Wnt signaling’, Volume 2, Pathway Models, Vol. 469, Methods in Molecular Biology, Humana Press, USA (2008). Editor, Dr E Vincan; Series Editor Prof J Walker. Book doi: 10.1007/978-1-60327-469-2